Zinc Prevents Sickness Behavior Induced by Lipopolysaccharides after a Stress Challenge in Rats
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منابع مشابه
Zinc Prevents Sickness Behavior Induced by Lipopolysaccharides after a Stress Challenge in Rats
Sickness behavior is considered part of the specific beneficial adaptive behavioral and neuroimmune changes that occur in individuals in response to infectious/inflammatory processes. However, in dangerous and stressful situations, sickness behavior should be momentarily abrogated to prioritize survival behaviors, such as fight or flight. Taking this assumption into account, we experimentally i...
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Recent studies have demonstrated the intimate relationship between depression and immune disturbances. Aware of the efficacy limits of existing antidepressant drugs and the potential anti-inflammatory properties of propentofylline, we sought to evaluate the use of propentofylline as a depression treatment. We used a rat model of depression induced by repetitive lipopolysaccharide (LPS) administ...
متن کاملThe effects of Nigella sativa on sickness behavior induced by lipopolysaccharide in male Wistar rats
Objective: Neuroimmune factors contribute on the pathogenesis of sickness behaviors. Nigella sativa (NS) has anti-inflammatory, anti-anxiety and anti-depressive effects. In the present study, the effect of NS hydro-alcoholic extract on sickness behavior induced by lipopolysaccharide (LPS) was investigated. Materials and Methods: The rats were divided into five groups (n=10 in each): (1) control...
متن کاملP45: The Effects of Nigella sativa on Sickness Behavior Induced by Lipopolysaccharide in Male Wistar Rats
Neuroimmune factors contribute on the pathogenesis of sickness behaviors. Nigella sativa (NS) has anti-inflammatory, anti-anxiety and anti-depressive effects. In the present study, the effect of NS hydro-alcoholic extract on sickness behavior induced by lipopolysaccharide (LPS) was investigated. The rats were divided into five groups (n=10 in each): (1) control (saline), (2) LPS (1 mg/kg, admin...
متن کاملthe effects of nigella sativa on sickness behavior induced by lipopolysaccharide in male wistar rats
objective: neuroimmune factors contribute on the pathogenesis of sickness behaviors. nigella sativa (ns) has anti-inflammatory, anti-anxiety and anti-depressive effects. in the present study, the effect of ns hydro-alcoholic extract on sickness behavior induced by lipopolysaccharide (lps) was investigated. materials and methods: the rats were divided into five groups (n=10 in each): (1) control...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2015
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0120263